Aspirin + Rosuvastatin + Clopidogrel is a combination of three medicines: Aspirin, Rosuvastatin and Clopidogrel, which prevents heart attack. Aspirin and clopidogrel are antiplatelet medications. They work by preventing the platelets from sticking together and decrease the formation of harmful blood clots. Rosuvastatin is a lipid lowering medication that blocks the body’s ability to produce “bad” cholesterol (LDL) and improves the level of "good" cholesterol (HDL).